The PFAS/PFOS problems are widespread, and I think much of the farmland contamination is concentrated in the upper Midwest, as Chicago and surrounding cities struggled to find a way to dispose of the sewage residues generated by the cities. When I lived in Illinois, they used to fill old strip mines with it. When the EPA declared it to an acceptable "organic" fertilizer, farmers believed they had found a cheap way to make their lands more fertile and the cities thought they had found a way to dispose of their waste. Michigan was the first to find the large-scale contamination and have stopped testing for contamination (last I heard) because of the lawsuits that were being generated. These "Forever Chemicals" are often used on medical devices to prevent the body from encapsulating them, so they are being directly implanted into our bodies. It is possible that these chemicals are responsible for some of the increase in chronic disease, but, for obvious reasons, there has been little real open research into the problems possibly generated by these things.